Stillbirths, Sudden Infant Deaths, and Long-QT Syndrome
نویسنده
چکیده
Stillbirths contribute substantially to perinatal mortality in developed countries.1 Their prevalence ranges between 4 and 6 per 1000 births.1–3 Despite careful investigation, at least 25%,4 and possibly 50%,1 remain unexplained. Another mysterious cause of early sudden death is represented by sudden infant death syndrome (SIDS),5,6 which is still the leading cause of mortality during the first year of life. Finally, a relatively large number of sudden deaths in the young (infants, children, and teenagers) is due to long-QT syndrome (LQTS).7–10 Are these entities completely unrelated or is there a link between them, such that the latter might be a contributor to the former? As a matter of fact, this specific hypothesis has already been proposed.11,12 Its interest lies in the fact that, beyond the scientific and conceptual implications, if proven correct it could offer an opportunity to prevent those fetal or infant deaths sharing the same genetic and arrhythmogenic mechanism.
منابع مشابه
Stillbirths, sudden infant deaths, and long-QT syndrome: puzzle or mosaic, the pieces of the Jigsaw are being fitted together.
Stillbirths contribute substantially to perinatal mortality in developed countries.1 Their prevalence ranges between 4 and 6 per 1000 births.1–3 Despite careful investigation, at least 25%,4 and possibly 50%,1 remain unexplained. Another mysterious cause of early sudden death is represented by sudden infant death syndrome (SIDS),5,6 which is still the leading cause of mortality during the first...
متن کاملSmoking and the sudden infant death syndrome: results from 1993-5 case-control study for confidential inquiry into stillbirths and deaths in infancy. Confidential Enquiry into Stillbirths and Deaths Regional Coordinators
متن کامل
The relationship between Tonic-Clonic sizures in children and increased time of ventricular repolarization
Background: Long QT syndrome (LQTS) is a disorder in which electrical cardiac ventricular repolarization is impaired. It results in an increased risk of an irregular heartbeat which can result in palpitations, fainting, drowning, or sudden death. Long QT Syndrome may present as tonic-clonic seizure or a seizure-like disorder. By taking a superficial electrocardiogram (ECG) and proper diagnosis,...
متن کاملLong-QT Syndrome
Copyright © 2008 Massachusetts Medical Society. After the sudden death of a 13-year-old girl while she was playing basketball, her family comes to the clinic for medical evaluation (Fig. 1). Her parents’ resting electrocardiograms (ECGs) are normal, but her 9-year-old sister’s ECG shows an abnormally long QT interval. There is a history of recurrent syncope in female relatives of the maternal g...
متن کامل57-58 Editoriale.qxd:-
Stillbirths contribute substantially to perinatal mortality in developed countries with a prevalence ranging between 4 and 6 per 1000 births (1-3). Despite careful evaluation during pregnancy of fetal well-being, about 25-50%, 1 remains without a clear cause, coding for a new entity called Sudden Intrauterine Unexplained Death Syndrome (SIUDS). Moreover, an important cause of early sudden death...
متن کامل